I'm not sure if any manufacturers other than Toyota offered a 4 cylinder 5MT 4x4. However, with a 5MT the smaller V6 (often around 3 liters) in each is probably decent, so you may not have to be limited to one brand.
To reduce the 4x4's hit on fuel economy you might lower it and put it on highway tread tires. Some 4x4s can be lowered for free; for example, those with torsion bar front ends. Look for torsion bars instead of coil springs.