Absolutely. In my previous Honda, I saw fuel economy differences of 5% - 13% among various highway tires, which meant some had lower rolling resistance than others. So if you go from an off road tire, which is almost certainly not a low rolling resistance (LRR) tire, to a highway tire, you should see significant FE improvements. And if you specifically select a LRR highway tire, the improvement should be even more substantial.
It's a LRR tire. I went through 2 sets of Nokians on my previous Honda (not the WR). Great handling, long tread life, LRR. Best tires I ever used. If you buy the Nokians and inflate them to the maximum sidewall pressure (likely 44 psi), I'll bet you'll get 15%+ better FE than you are now.
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I'd go with a Highway All-Season tire on a Silverado. Like beatr911 mentioned, the BFG Long Trails are pretty nice. I had them on my old S-10 p/u. They did loose traction rapidly when I was down to 5/32nds, however. The Yokohama Geolander H/T-S G051s are another nice choice, IMO. You may not be able to reap the full benefits that a passenger car would w/LRR tires....but its a good start!
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LRR tires is a good start. but,even @ 5 or 10% gain, you won't see much in your FE w/ that vehicle.
look in the archives for truck threads. grill block, airtabs,driving techniques, etc will help you as well.
I put narrower tires on my F350, and it seemed to help about 1 mpg or so. The original tires were 265 75R16 BFG Long Trail. The new tires are Michelin 235-85R16 M&S tires. The new tires are a tad taller, just 0.3". They don't have a very aggressive tread, but they did well last winter. Never got stuck.
I'm going to northern Maine next week, off road. I hope they do OK on muddy and snowy dirt roads.
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The knobby off-roaders generally have a high resistance. Comsumer Reports has the latest report on tire RR, but you have to pay to use it.
I have Michelin MXV-4 "Green-X" LRR treads on the 'Teg. Overpressure and this tread design really helped boost FE. Judging from my Gaslogs, I would say that it helped in the 5-10% range, plus or minus. They're a bit pricey, but I don't worry so much putting 50 psi in them. One-year of use and they're great.
just prove where airtabs work and i'll set my rock down
never tested them. but, i can SHOW you that acetone,for example, DOES(my car) and DOES NOT work(wife's car). if you don't come see it, you'll have to take my word(tested #s)for it. or not, the choice is yours.
i understand your skepticism tho. i'm a "seeing is believing" kinda guy.
BUT, remember...don't believe anything ya hear, and only half of what ya see!